My lab investigates how blood pressure can be treated more effectively. Much of that work involves the painstaking development of new concepts and research methods to move forward the state of the art. For example, our work on urinary extracellular vesicles’ mRNA as an ex vivo assay of the ligand-activated transcription factor activity of mineralocorticoid receptors is challenging, fun, and rewarding. With a lot of work from Andrea Berrido and Pradeep Gunasekaran in my lab, we have been moving the ball forward on several key projects on that front.